High-speed sample injections can significantly improve throughput in multi-sample processing, especially for analyses with short runtimes. Recently, a novel high-speed autosampler was introduced that features an injection time of just 7 seconds and an analysis cycle time of 14 seconds. The combination of this autosampler with core shell and small particle columns allows ultrahigh throughput to be achieved without any specialized instrument routines that add complexity to the analysis.
Analytical runs were evaluated with UV and a high-speed quadrupole that features a positive/negative ionization switching time of 15 msec and a high-speed scanning rate of 15,000 u/sec under ultra-high throughput conditions of up to four analytical runs per minute.