Drug release behavior is analyzed with dissolution testing, which simulates the behavior of capsule, bead, and enteric-coated tablets in vitro. Examples of the most popular dissolution apparatus include the paddle apparatus and the reciprocating cylinder, which are utilized in the dissolution studies of extended-release products.
Key considerations for purchasing dissolution equipment include the formulation of the compound, the type of reagents required for dissolution testing, the particular excipient utilized in the formulation, laboratory conditions, and regulatory compliance requirements.
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Company | Pion Inc. | Pion Inc. | Pion Inc. |
Item | µDISS Profiler Small Volume Dissolution and Solubility Apparatus | Rainbow Dynamic Dissolution Monitor | Spectra Dynamic Dissolution Monitoring |
Price | Inquire | Inquire | Inquire |
Vendor Product Page | Company Product Page | Company Product Page | Company Product Page |
Dosage Form | Powders, Suspensions, Liquids | Tablets, Capsules, Suspensions, Liquids | Tablets, Capsules, Suspensions, Liquids |
Speed | 8 Channel Parallel | 8 Channel Parallel in 2 Seconds | 8 Channel Parallel in 30 Seconds |
Type | Miniaturized in-situ Concentration Measurements | In-situ Dissolution Monitoring Based on Fiber Optic UV | In-situ Dissolution Monitoring Based on Fiber Optic UV |
Temperature Range | Ambient to 40c° | Wide Temperature Range | Wide Temperature Range |
Description | Versatile in situ UV measurements for evaluation of various effects on solubility, dissolution, supersaturation and precipitation profiles.
The µDISS Profile™ is a versatile instrument for measuring concentration in real time with fiber optic | Real time in situ UV dissolution measurements for laboratories from R&D through manufacturing
The Rainbow is a powerful tool for accurate dissolution analysis without the high cost, extensive maintenance, operator involvement, and slow turnaround | Real time in situ UV dissolution measurements for laboratories from R&D through manufacturing
The Spectra is designed for accurate, real-time, maintenance-free QC dissolution testing. This new system maximizes value without sacrificing performance. |
Get quote | Inquire | Inquire | Inquire |