American Pharmaceutical Review: A Russell Publishing Publication

Winter 2002

Articles

• Automated Liquid Chromatography MALDI FT-ICR MS Platform for Proteomics: Automated High Performance Mass Spectrometry and Data Analysis

  Ansgar Brock*, David M. Horn, Christopher M. Shaw, Eric C. Peters, Christer Ericson, Qui Phung, Scott B. Ficarro, Arthur R. Salomon, *Genomics Institute of the Novartis Research Foundation

• Barrier Isolation Technology Can Improve Life Sciences Cleanroom Applications

  Scott E. Mackler, Cleanroom Consulting, LLC

• Conducting Sponsor Audits and Evaluations of Clinical Service Providers for Compliance with 21 CFR Part 11

  Angela Berns, Amgen, Inc.

• Counterfeit Drugs: A New Paradigm for Security

  Joseph F. Noferi, Esq., Edward R. Arling and Ralph L. Dillon, Pharmacia Corporation

• Development and Application of Single-Column Direct Plasma Injection Procedures for Drug Candidate Assays Using HPLC-MS/MS

  Yunsheng Hsieh*, Ph.D., Kwokei Ng, Ph.D., and Walter A. Korfmacher, Ph.D., Drug Metabolism and Pharmacokinetics Department, Schering-Plough Research Institute

• Ensuring Robust Polymorph Isolation Using In-Situ Raman Spectroscopy

  George Zhou, Ph.D., Jian Wang*, Ph.D., Zhihong Ge, Ph.D., Yongkui Sun, Ph.D.,Merck Research Laboratories, Merck & Co., Inc.

• Freezing and Annealing Phenomena in Lyophilization: Effects Upon Primary Drying Rate, Morphology, and Heterogeneity

  Theodore W. Randolph, Ph.D.1 & James A. Searles, Ph.D.2, 1University of Colorado, Boulder, 2Eli Lilly & Co.

• Growth of Near-Infrared Spectroscopy in Pharmaceutical and Medical Sciences

  Emil W. Ciurczak, Consultant

• Lipid-Based Systems for Oral Drug Delivery: Enhancing the Bioavailability of Poorly Water Soluble Drugs

  David J. Hauss, Ph.D., Eli Lilly and Company

• Meeting the Challenges of Viable Delivery Systems for Peptide and Protein Pharmaceuticals

  Stanley S. Davis, Ph.D., Institute of Pharmaceutical Sciences, University of Nottingham

• Mining Gene Expression Data: A Review of Gene Expression Methodology and Analysis in Drug Discovery

  Sherri Matis, Ph.D., Nick Brown and Gayathri Ramabadran, AstraZeneca Pharmaceuticals

• Paperless Laboratories – They’re Inevitable!

  Glenn Van Buskirk, Ph.D., Thomas P. Layloff, Ph.D., Jerome P. Skelly, Ph.D., & Francis H. Zenie

• Steps for Development of a Dissolution Test for Sparingly Water-Soluble Drug Products

  Carol Noory, Nhan Tran, Ph.D., Larry Ouderkirk, and Vinod Shah, Ph.D., Food and Drug Administration, Center for Drug Evaluation and Research

• Taste Masking Science and Technology Applied to Compacted Oral Solid Dosage Forms – Part

  Joseph P. Reo, Ph.D. and Jennifer K. Fredrickson, Pharmacia Corporation

• The Application of Thermoanalytical Techniques to the Study of the Freeze-Drying Proces

  Vicky Kett, Ph.D,.The School of Pharmacy, Queen's University of Belfast