American Pharmaceutical Review: A Russell Publishing Publication

July/August 2007

Articles

• Pushing the limits of SFC to resolve chiral molecules

  Christina Kraml Lotus Separations

• Particle Engineering using Supercritical Fluid Technology: Application to the Control of Dissolution Rate of Drugs

  Joel Richard MerckSerono

• Investigation of Contaminants in Protein Pharmaceuticals in Pre-Filled Syringes by Multiple Micro-Spectroscopies

  Zai-Qing Wen*, Gianpiero Torraca, Chanel Yee and Guiyang Li Department of Global Cellular and Analytical Resources Amgen Inc.

• Salt and Polymorphism Screening of High Potency Compounds: Modern Methods and Safe Handling

  Nicolas Giroud, Christoph Saal, Dirk Wandschneider and Michael Maiwald Merck KGaA, Darmstadt, Germany

• Spatially Resolved Characterisation of Dosage Forms Using Novel Thermal Probe Techniques

  Duncan Q.M.Craig and Mike Reading School of Chemical Sciences and Pharmacy University of East Anglia, UK

• Regulatory Aspects of the Use of New Particle Engineering Technologies

  Robert A. Lionberger Office of Generic Drugs Food and Drug Administration

• Test Method Validation for Cleaning Validation Samples

  Richard J. Forsyth Associate Director in Worldwide GMP Quality Merck & Co., Inc,

• The Significance and Detection of VBNC Microorganisms

  Dr. Paul Newby Team Leader, Pharmaceutical Microbiology, GlaxoSmithKline

• A Forced Degradation Strategy: How Johnson & Johnson PRD Approaches Forced Degradation

  Rhonda A. Jackson, Ph.D. Johnson & Johnson Pharmaceutical Research and Development, L.L.C.

• Use of In Vitro Lipid Digestion Models for Assessing Oral Lipid Formulations

  Leab Sek Merck Sharp & Dohme

• The Future of Peptides in the Treatment of Obesity

  Lianshan Zhang and John P. Mayer Lilly Research Laboratories

• Towards Imaging-Guided Gene Therapy of Malignant Glioma

  Alexandra Winkeler and Andreas H. Jacobs Max Planck-Institute for Neurological Research, Center for Molecular Medicine Cologne (CMMC) and Department of Neurology, University of Cologne and Klinikum Fulda, Germany

• Development of Oral Suspensions

  Guang Wei Lu, Ph.D. Parenteral Center of Emphasis, PGRD, Pfizer

• Is PAT changing Product/Process Development?

  S. Sonja Sekulic, PhD Pfizer Global Research & Development

• On-Line Monitoring of Industrial-Scale Blending Processes Using NIR: An Overview from System Selection to Measurement in GMP Environments

  Chi-Shi Chen1 and José Montenegro Alvarado2 1 Pfizer’s Global Manufacturing Division, Process Analytical Support Group (PASG) 2 Pfizer’s Global Manufacturing Division, Caguas Site