The HEK293 cell line is one of the most widely used in the production and manufacturing of various biologics, from recombinant proteins to viral vectors. It is critical that residual host cell DNA is minimized in the final drug substance to ensure product quality and patient safety.
Regulatory authorities around the world including the WHO, EMA and the US FDA, therefore, limit the amount of residual host cell DNA allowed in the final drug product.
A highly sensitive, rapid method to quantify residual host cell DNA is important to ensure clearance by the purification process and for lot-release testing. Yet developing a home-brew assay can be resource intensive and risky as they usually rely on various component vendors.
In this webinar we will share the design, performance, and workflow implementation of a highly sensitive, robust, off-the-shelf solution to specifically quantitate the residual host cell DNA from HEK293 cells designed to meet regulatory requirements.
In this webinar you’ll learn:
Who should attend: