Endogenous Mechanisms for Nanoparticle-Based Nucleic Acid Delivery

Previously Aired on January 30th, 2024

Sign Up:

(*) denotes required form field(s)

Our registration process uses cookies, by submitting this registration form you agree to our cookie policy.

  Register

Overview

Nucleic acid delivery to specific tissues and cells is very challenging. To address the delivery barriers, a variety of nanoparticle formulations, including lipid nanoparticles, have been tested. In this presentation, we will focus with case studies on endogenous mechanisms that can enhance nucleic acid delivery to their target – especially extrahepatic delivery.

Three strategies - role of protein corona, use of cells as Trojan Horse, and extracellular vesicles – will be discussed.

In this webinar you’ll learn:

  1. Ascendia’s expertise and capabilities in NPs
  2. Role of protein corona on tissue and cell-specific targeting
  3. Peritoneal macrophage tropism to disease sites
  4. Extracellular vesicle-mediated in vivo delivery

Who should attend:

  • Industrial Pharmaceutical Scientists- (Manager, VP, CSO, CTO)
  • Academic Pharmaceutical Scientists – (MS/PhD Students, Postdocs)
  • Consultants

Presenters

Presenter
Shaukat Ali, PhD, FAAPS
Sr. Director Scientific Affairs & Technical Marketing
Ascendia Pharmaceuticals
View Biography
Presenter
Mansoor M. Amiji, PhD, FAAPS, FCRS
University Distinguished Professor, Professor of Pharmaceutical Sciences, and Professor of Chemical Engineering,
Northeastern University
View Biography
Presenter
Mike Auerbach
(Moderator)
Editor-in-Chief,
American Pharmaceutical Review