Drug delivery is the method or process of administering a pharmaceutical compound to achieve a therapeutic effect. A drug’s efficacy is impacted significantly by its method of delivery.
When creating a novel drug, understanding of the physiological barriers to efficient delivery, such as drug transport in the circulatory system and its movement through cells and tissues is paramount. Drug delivery systems consist of the delivery route, delivery vehicle and dosage form.
Drug Delivery Routes
- Buccal
- Oral
- Pulmonary
- Transdermal
- Ocular
- Nasal
- Sublingual
Drug delivery vehicles can improve the efficiency and safety of therapeutic agents by managing pharmacokinetics and pharmacodynamics. Numerous drug delivery vehicles have been developed with various sizes, architectures, characteristics and surface properties.
Drug Delivery Vehicles
- Nanoparticles
- Liposomes
- Lipoproteins
- Macromolecules
- Microspheres
- Live Viruses
Drug delivery systems influence the release rate of a drug and the location in the body where it is released. By testing a variety of drug delivery systems it is possible to achieve better pharmacokinetics, pharmacodynamic, immunogenicity, and efficacy of drugs while reducing toxicity and side effects.
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