Pharmaceutical Permeability Test Equipment

Permeability testing is used to profile the permeation behavior of pharmaceutical compounds. The many factors affecting permeability such as pH or hydrophilicity can make it difficult to perform an in-vitro assay for determining a permeability coefficient. A new generation of permeability testing equipment is able to simulate in-vitro drug permeability behavior without the expense or approval time of actual in-vitro studies. A PAMPA (parallel artificial membrane permeability assay) test can simulate permeability across different membranes by creating a specific lipid charge. In-vitro permeability models can simplify studies and reduce research costs for examining blood-brain barrier or intestinal drug permeation.