Cell Culture Technologies and Products

Growth factors are the unique cell signaling molecules that play important roles in cell proliferation and development. It's a fact that cell cultures can greatly benefit from the use of pure, high quality proteins. The addition of growth factors to cells in culture provides the appropriate environment for cell health and growth. Selecting the right growth factors and cytokines for your application is an important task. Some fastidious cells need serum-free media that often necessitates the use of certain growth factors and cytokines. This is always true for primary cells but often necessary for transformed cell lines and hybridomas as well. Growth factors include enzymes, antigens, specialized proteins, inhibitors, stem cell factors, binders, stimulating factors. Purchasing considerations include the origin of the growth factors, the necessary amount, the intended usage, the storage requirements, and the regulatory status governing experimental requirements.

Pharmaceutical Application of Cell Lines and Cell Culture Technology

• Research and development of drug application and toxicity
• As models for certain disorders and for studying certain types of diseases
• In testing and creating biotherapeutic treatments for hereditary illnesses
• In testing and developing vaccines

Purchasing Considerations for Pharmaceutical Cell Lines

• Prospective application of chosen cells in testing
• Specific requirements restricting the use of human-origin cells (scientific, regulatory, etc.)
• Genetic stability of the cell line (to maintain consistency throughout research and production)
• Specific origin of the cell line (e.g., is it organ derived, tissue derived?)
• Other factors about the cell line that will have to be monitored closely in its application to research (e.g., does it have oncogenic capacity in research animals? Can it be affected by common viruses?)
• Additional equipment and reagents required for handling cell culture products
• Expected length of research