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| Company | Gattefossé | Gattefossé | Gattefossé | Gattefossé | Gattefossé |
| Item | Gelucire® 44/14 | Labrasol® | Labrasol® | Labrasol® ALF | Transcutol® HP |
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| Vendor Product Page | Company Product Page | Company Product Page | Company Product Page | Company Product Page | Company Product Page |
| Description | Lauroyl polyoxyl-32 glycerides NF / Lauroyl macrogol-32 glycerides EP / Lauroyl macrogolglycerides (32) Ch P | Caprylocaproyl polyoxyl-8 glycerides NF | Caprylocaproyl polyoxyl-8 glycerides NF / Caprylocaproyl macrogol-8 glycerides EP | A nonionic water-dispersible liquid surfactant for lipid-based formulations, Labrasol® ALF is used to solubilize and increase oral bioavailability of poorly water-soluble APIs. Its ability to self-emulsify in aqueous media enables it to form | A high-purity liquid solvent, Transcutol® HP can be used as a powerful solubilizer, penetration and bioavailability enhancer in oral and parenteral routes, and excellent cosolvent in self-emulsifying formulations. Transcutol® HP conforms to |
| Final Dosage Form | Capsules, emulsions, suspensions | Oral, Topical, Transdermal | Oral, Topical, Transdermal | Capsules, emulsions, suspensions, gels, foams, creams, lotions, ointments | Capsules, solutions, emulsions, suspensions, creams, lotions, ointments, gels |
| Functionality | Solubilizer, bioavailability enhancer, and surfactant in solid dispersions and SMEDDS | Solubilizer, Bioavailability enhancer, Surfactant in capsule filling, SMEDDS, Solutions, Suspensions, Topical Penetration and Permeation enhancer, Processing aid | Solubilizer and O/W surfactant for microemulsion. Able to form light foams with pump device (no gas required). | Water disperible surfactant, solubilizer and bioavailability enhancer in SMEDDS, topical penetration/permeation enhancer, able to form light foams with pump device (no gas required), low impurities guaranteed for stability and capsule compatibility | High purity solvent for all types of dosage forms, capsules, injectables, co-solvent in SMEDDS, solutions, suspensions, topical penetration and permeation enhancer |
| Pharmacopeial Compliance | Yes | Yes | Yes | Inquire | Yes |
| Type | Block | Liquid Surfactant | Inquire | Liquid | Liquid |
| Application | Oral | Solubilizer, Bioavailability enhancer, Surfactant in capsule filling, SMEDDS, Solutions, Suspensions, Topical Penetration and Permeation enhancer, Processing aid | Water dispersible surfactant, Solubilizer, Bioavailability enhancer, Component of SELF, Topical penetration/permeation enhancer | Oral, Topical, Transdermal | Oral, Topical, Transdermal, Parenteral |
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