White Paper: Micro Scale Separation: Optimizing the Bio-Rad NGC Chromatography System for Cryo-EM

Structural biology is the three-dimensional study of complex biological molecules, like proteins, to determine their structures at atomic resolution. The structural characterization of complex proteins gives researchers a glimpse into their in-vivo mechanistic functions and complex novel chemistries. In the case of drug development, structural information of proteins involved in disease pathways is crucial for downstream rational design of novel therapeutics. The field of structural biology is currently undergoing a renaissance due to significant advances in cryogenic electron microscopy (cryo-EM) with the emergence of direct electron detectors and advanced computational platforms. Protein structures can now be determined to the near-atomic level using this technique and many researchers are looking to add cryo-EM into their research repertoire.

Download the Document

    * denotes a required field

    Please fill out the information below. If you are already registered, and this information will be filled out for you.

  • Please enter your first and last name.

  • Please enter the name of the company or institution you work at.

  • Please enter your mailing address.

  • Please enter the e-mail address you would like to be contacted at.

  • Please enter the phone number you would like to be contacted at.

    • By submitting this form, you consent to American Pharmaceutical Review storing your email address and contact information and transmitting your contact information to the content sponsor. You may request to be removed at any time.