This webinar will cover theory and application of in-situ forming extended-release bioresorbable polymer technology for parenteral applications.

Ashland will explain control mechanisms coupling theoretical chemistry with formulation knowledge in a range of formulation formats for successful extended-release drug delivery from days up to several months. Ashland’s team will demonstrate how customized chemistry can overcome technical challenges.

Indivior will explore the advantages of in-situ forming depots and illustrate how depot formation and degradation mechanisms impact active pharmaceutical ingredient blood plasma concentrations. The team will also provide case studies on 2 FDA approved long acting injectables, taking the audience from initial development objectives through clinical data with the final finished product.

Learning Objectives/Outcomes for Attendees:

Develop an understanding of:

• How chemistry controls are utilized to affect change in performance
• Ashland Viatel™ bioresorbable polymer chemistry platforms
• Mechanisms of release and advantages of delivery formats that have been successful in the market including in-situ forming systems, solid implants and particle technologies as well as an understanding of new delivery formats being explored
• Challenges and strategies that exist for a bioresorbable polymer based extended-release technology with highlights of past-learning outcomes
• Common sterilization and processing options

• Pharmaceutical scientists
• Formulators
• Manufacture engineers
• Strategists
• Stakeholders with an interest in long-acting drug formulation