Pall Life Sciences Introduces New Technologies for Scalable Bioprocess Optimization

Pall Corporation announced the following new additions to the Allegro single-use chromatography and Cadence continuous bioprocessing product portfolios. Each product enables scalable process integration and intensification for biopharmaceutical manufacturers, while reducing resource use, process time, user risk and overall facility footprint.

Allegro Single-Use Chromatography System: The latest addition to the industry's first complete, automated platform of scalable single-use solutions—R&D to process scale—will be previewed during the BPI event. The flexible single-use chromatography system design enables installation of two different sized manifolds, with a flow range of 10 to 900 L/h. In addition, the system can accommodate applications utilizing membrane chromatography.

Cadence BioSMB Process 80 System: This modular 80 liter/hour process scale continuous multi-column chromatography system has been built specifically to support small scale process development, with perfusion bioreactor-based compatibility.

Cadence BioSMB Process 350 System: This modular 350 liter/hour process scale continuous multi-column chromatography system allows for scalable process flexibility, while still delivering the advantages of minimized facility footprint and resource consumption. It has been designed for fed batch applications of up to 2000L.

Cadence Virus Inactivation System: Designed to complement the Cadence BioSMB Process 80 and 350 systems, this fully automated low pH virus inactivation system can be integrated into batch, semi- or fully continuous processes.

"A changing market has increased demand for drug manufacturers to innovate, thereby driving the need for critical automated end-to-end traditional and single-use process solutions. This is especially true as many manufacturers look to pursue the advantages of semi- or fully-continuous bioprocessing approaches," said Martin Smith, Pall Chief Technology Officer. "The latest additions to our technology portfolio provide the support manufacturers need, and carry forward Pall's promise to bring continuous bioprocesses to life. We are happy to introduce these new technologies to the industry during BPI 2017 this week."

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