Bosch Packaging Technology and Parsolex have entered into a close cooperation on solid dosage manufacturing.
“Our strategic partnership with Parsolex showcases our state-of-the-art oral solid dose manufacturing equipment and, combined with their wealth of expertise, this will position Parsolex as a top contract manufacturer for the pharmaceutical industry,” Thomas Mauritzen, president of the Bosch Packaging Technology pharma division in North America, said.
Parsolex has chosen Bosch Packaging equipment for its recently expanded CGMP commercial manufacturing facility in West Lafayette, Indiana, to complement its existing capabilities. The company believes that the new Bosch Packaging machines will contribute to a range of clinical supply manufacturing programs.
“Parsolex is excited to partner with Bosch Packaging Technology to offer our clients access to the latest solid dosage technology innovations in granulation, coating, tablet compression and capsule weight sorting,” said Alfonso Chang, CEO of Parsolex. “Access to Bosch Packaging and its technology enhances our capability to work on even more complicated and/or diverse issues that are challenging our clients’ business today.”
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The new Bosch Packaging precision equipment installed at Parsolex’s West Lafayette site includes:
- The Pilotmix and Pilotlab platforms, which offer new granulation and precision coating capabilities, including high-shear and spray granulation, as well as fine particle, pellet and microtablet coating and drying, respectively. Additionally, this CGMP granulation suite is equipped with pneumatic material transfer capabilities for closed product transfer to increase production efficiency and offer solutions for optimal particle size distribution, including milling and sieving dry and wet powders.
- TPR 200 tablet press, which more than doubles Parsolex’s tablet compression production rate and allows for greater flexibility, improved yields and faster changeover times.
- Solidlab 2 drum coater, which can scale up production parameters for cosmetic and functional film compressed tablet cores coating, including controlled release applications.
- KKE 1700 capsule checkweigher, which offers 100% gravimetric capsule weighing and maximum output.
The new equipment utilizes Bosch Packaging’s modular data acquisition systems, which will help Parsolex to develop process parameters and improve their statistical process control. Parsolex will also benefit from Bosch Packaging’s experience in software design, with a focus on GAMP 5 guidelines. In doing so, Parsolex will comply with the 21 CFR Part 11 requirements.
As part of the strategic partnership, Bosch Packaging Technology and Parsolex will conduct joint research projects that demonstrate Parsolex’s capabilities on Bosch Packaging Technology’s machines.