Pharmaceutical freeze drying or lyophilization is a technique used in the research, development, manufacturing, and transport of drug substances. Freeze drying is commonly employed to overcome stability barriers in labile products and common uses of lyophilization are seen in the creation and storage of room temperature products. Freeze-dried products can have extended shelf lives which benefit benefits for research and manufacturing.
Lyophilization in biopharmaceutical development involves sublimation, by which proteins, antibodies, or other drug and drug-related substances are converted from a solid phase directly to a gaseous phase.
When choosing a freeze drying machine for your lab or manufacturing environment, you’ll want to ensure you have the right lyophilizer for the job. For example, special care must be taken to preserve the biological integrity when using lyophilization in microbiology.
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