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When looking at ways to optimize or retrofit a facility design, cleanroom classifications have typically remained fixed due to legacy thinking. Quite simply, the benefits of downgrading cleanroom ...
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Disinfection of pharmaceutical facilities represents a critical element of contamination control.1 With disinfectant efficacy testing, the surface or coupon (carrier) test is by far the most ...
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My first real job after graduating college, back at the dawn of time, was as an editor for a twice-weekly newspaper that reported on current or upcoming construction projects. Our readers, who were ...
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The purpose of this column is to highlight
and summarize recent key patents in the
pharmaceutical arena issued by the US
Patent Offi ce in January-February, 2024.
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During my consulting practice, I get many requests from clients to evaluate non-target bacteria isolated during tests for specified microorganisms. Although I appreciate the business, these requests ...
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The Drug Supply Chain Security Act (DSCSA) went into effect on November 27, 2023, despite what you may have heard about a one-year extension until November 2024. All stakeholders along the supply ...
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Achieving targeted delivery of nucleic acids to specific tissues and cells presents a challenging obstacle in biomedical research and therapeutic development. Overcoming these barriers necessitates ...
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The effect of food as part of the daily diet on drug absorption has been noted since the 1960s (Sjoqvist, 2010). Food can either increase or decrease the oral bioavailability of drugs, potentially ...
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In the development of New Chemical Entities (NCEs), their low aqueous solubility will drastically affect their bioavailability. Understanding at an early stage the behavior and characteristics of ...
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The field of clinical gene therapy has advanced rapidly and now accounts for over 2,200 clinical trials initiated since 1989, of which ~65% are being conducted in the USA. Progress in the field has ...
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