Company Description
Thermo Fisher Scientific Inc. is the world leader in serving science, with revenues of more than $20 billion and approximately 70,000 employees globally.
We provide complete workflows, from cryo-EM structural determination of macromolecular complexes in native state to 3D reconstruction of tissues and cells. Our leading cryo-electron microscopes allow to determine structures of proteins and macromolecular complexes at near-atomic resolution. This enables scientists to study how biomolecules function and interact, helping them to understand disease mechanisms and allowing for targeted drug discovery.
Our solutions help reveal protein function and the cellular process, bridging the gap between basic science and translational therapeutics.
Company Background
In 2016, FEI Company, the leader in high-performance transmission and scanning electron and ion microscopy including cryo-electron microscopy (cryo-EM) became a part of Thermo Fisher. Our leading electron microscopy workflows provide images and information at the micro-, nano- and picometer scales.
Products & Services
Researchers are using Thermo Scientific™ cryo-EM instruments to study neurodegenerative diseases, such as Alzheimer’s, Parkinson’s, Huntington’s; as well as cancers, HIV, malaria, the Zika virus disease, or diabetes, cardiovascular and others.
Our instruments allow for insights into biological mechanisms that have been inaccessible by previous methods:
- The Thermo Scientific Glacios™ cryo-TEM is a purpose-built and efficient option for organizations entering into cryo-EM single particle analysis (SPA) and offers a complete cryo-EM solution for high resolution data collection on routine samples.
- The Thermo Scientific Krios™ G4 cryo-TEM is the most advanced cryo-EM instrument on the market for protein structure determination.
More than 90% of cryo-EM reconstructions with resolutions better than 4A in the Protein Data Bank and the Electron Microscopy Data Bank were developed on a Thermo Scientific instrument.