Retrophin announced the Company has changed its global corporate name to Travere Therapeutics, Inc. In conjunction with the name change, the Company expects to begin trading under the new ticker symbol "TVTX" on the Nasdaq Global Select Market at market open on November 19, 2020.
“Over the last several years we have emboldened a patient-inspired mindset in all aspects of our organization, and championed our mission of identifying, developing and delivering life changing therapies to people living with rare disease,” said Eric Dube, Ph.D., chief executive officer of Travere Therapeutics. “We developed this new name to reflect our commitment to forging new paths with patients to deliver hope and innovation, and to honor our remarkable evolution. As we enter an exciting period of our journey led by the promising future of our pipeline of potential first-in-class therapies, now is the right time to transition to Travere Therapeutics.”
The name Travere (pronounced “truh-veer”) Therapeutics represents the Company’s commitment to being a trusted partner to patients and their communities as they face the ever-changing path of living with rare disease. Its patient-inspired approach is captured in its new tagline, “In rare for life,” which speaks to the Company’s dedication to working with the rare disease community to make a positive impact on the many aspects of patients’ lives, beyond delivering life-changing treatments.
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Travere Therapeutics is advancing therapeutic candidates for rare disorders in nephrology, hepatology and metabolism; sponsoring no-cost genetic testing aimed at improving the diagnostic odyssey for children born with cholestasis; partnering with patient advocacy organizations to meet the diverse needs of patients and their families; and ensuring broad access and education for its FDA-approved therapies.
The Company’s pipeline is led by sparsentan, which is being investigated in pivotal Phase 3 clinical trials for rare kidney diseases - focal segmental glomerulosclerosis (FSGS) and IgA nephropathy (IgAN). The DUPLEX Study in FSGS and the PROTECT Study in IgAN are both positioned for topline readouts from the proteinuria endpoints next year. Travere Therapeutics recently expanded its promising pipeline with the addition of OT-58, now called TVT-058, an investigational human enzyme replacement therapy in Phase 1/2 development for the treatment of classical homocystinuria. Travere Therapeutics continues to partner with leaders in patient advocacy and the National Institutes of Health on early research in rare metabolic and hepatic conditions - NGLY1 deficiency and Alagille syndrome.
As part of its commitment to patient communities, Travere Therapeutics supports the Children’s National Rare Disease Institute’s efforts to improve access and establish global best practices in diagnosing and treating rare diseases. It recognizes the needs of caregivers by collaborating with the National Organization of Rare Disorders to launch and support the Rare Caregiver Respite Program.
The Company leads efforts to make health equity a priority, particularly among those in underrepresented communities with rare disease. Travere Therapeutics helped form and is a sponsor of the Rare Disease Diversity Coalition, led by the Black Women’s Health Imperative, to address disparities in the healthcare system, access issues, education and affordability. In addition, it worked with the EveryLife Foundation to create their first-ever Diversity Inclusion Advocacy Fellowship for Rare Diseases.