Alveolus Bio announced a strategic scientific collaboration with BiomEdit, an emerging animal health biotechnology company leveraging microbiome science and synthetic biology to develop novel products to prevent and treat disease in animals. BiomEdit, founded in 2022, originated through a carveout from Elanco Animal Health, formerly a division of Eli Lilly, in a strategic partnership with Ginkgo Bioworks.
Central to this collaboration is the sharing of resources and expertise. Alveolus Bio will be studying BiomEdit's proprietary consortium of commensal strains, which secrete metabolites with documented anti-inflammatory and immune-modulating properties. In controlled in vivo studies, the strains have demonstrated a capacity to reduce viral titer in avian coronavirus challenges. Alveolus Bio aims to further research this novel consortium in the context of influenza viral infections in humans.
In turn, BiomEdit will explore the application Alveolus Bio's resMIT (respiratory microbiota-based inhaled therapeutics) platform. This platform has been developed to engineer inhalable drug particles for effective delivery into the deep lung regions. BiomEdit, with its current pipeline consisting of natural bioactives, commensal bacteria consortia, and engineered microbes, views Alveolus' inhaled therapeutics as having unique potential in the development of respiratory therapeutics in companion animals.
Both companies emphasize their commitment to evidence-based research, with the primary goal of expanding the potential of biotherapeutic applications leveraging an advanced understanding of the microbiome.
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