Description
A nonionic water-dispersible liquid surfactant for lipid-based formulations, Labrasol® ALF is used to solubilize and increase oral bioavailability of poorly water-soluble APIs. Its ability to self-emulsify in aqueous media enables it to form fine dispersions, microemulsions, and self-emulsifying drug delivery systems (SEDDS).
Labrasol® ALF consists mainly of PEG-8 mono- and diesters of caprylic (C8) and capric (C10) acids with a small fraction of mono-, di- and triglycerides, and it conforms to US and European monographs for Caprylocaproyl Polyoxyl-8 glycerides NF and Caprylocaproyl macrogol-8 glycerides EP. Its high purity is guaranteed for stability and capsule compatibility, and precedence of use in approved pharmaceutical products makes Labrasol® ALF an ideal candidate for capsule formulations.