Lubrizol's Carbopol® polyacrylic acid polymers (carbomers) have been used in commercial pharmaceutical and nutraceutical formulations for decades as:
- Highly efficient matrix formers for ER tablets
- Best-in-class suspending agents for oral liquids
- Taste-masking ingredients for pediatric drug delivery
- Excellent mucoadhesive polymers for tablets, liquids, and semi-solids
Benefits of Carbopol polymers for oral drug delivery include:
- Ability to produce multimedia compliant, controlled release oral solid dose formulations in combination with a broad spectrum of active pharmaceutical ingredients (APIs), buffering agents, and/or co-excipients
- Highly efficient gel matrix formation at low polymer usage levels
- Synergies with traditional matrix formers such as HPMC, allowing for better control over drug release with lower total polymer usage
- Ability to produce smaller, easier to swallow tablets, even with a high dose of API
- Permanent suspension with broad flavor and preservative compatibility for oral liquids
- Versatile processing options, such as direct compression (Carbopol 71G NF) and wet and dry granulation
- Global pharmacopoeial and regulatory compliance
Lubrizol's excipients for oral drug delivery offer excellent physical properties, such as tablet hardness and low friability over a wide range of compression forces, and come in both powder and granular forms. Our excipients are manufactured under GMPs in ISO:9001 certified facilities, have established DMFs, and have been extensively tested for biocompatibility and safety.