The Kinetic-QCL™ assay is a quantitative, kinetic assay for the detection of Gram negative bacterial endotoxin. A sample is mixed with the LAL/substrate reagent, placed in an incubating plate reader, and monitored over time (via WinKQCL™ Software) for the appearance of a yellow color.
It is the chromogenic nature of the Kinetic-QCL™ assay that makes it the most appropriate choice for testing small volume parenterals, vaccines, antibiotics and biologicals. The Kinetic-QCL™ assay is less impacted by inhibitory products which may interfere with the clotting mechanism in Turbidimetric and Gel Clot assays. With a sensitivity range of 0.005 EU/ml - 50.0 EU/ml, the Kinetic-QCL™ assay is the most sensitive of the LAL assays. Multiple samples can be processed at one time in this 96-well format resulting in time savings in a busy laboratory. An incubating plate reader is required to run this assay.