HPLC detectors fall into two main categories: universal or selective. Universal detectors typically measure a bulk property (e.g., refractive index) by measuring a difference of a physical property between the mobile phase and mobile phase with solute while selective detectors measure a solute property (e.g., UV-Vis absorbance) by simply responding to the physical or chemical property of the solute. HPLC most commonly uses a UV-Vis absorbance detector, however, a wide range of other chromatography detectors can be used. A universal detector that complements UV-Vis absorbance detection is the Charged aerosol detector (CAD).
Refractive index detectors are commonly used in HPLC. This detector provides readings by measuring the changes in the refractive index of the eluent as it moves through the flow cell. In certain cases, it is possible to use multiple detectors, for example, LCMS normally combines UV-Vis with a mass spectrometer.
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- Type: UV/VIS detector
- Pharmaceutical Application: Photometric determination of light-absorbing substances in the
UV/VIS range.It serves as UV/VIS detector within an ion chromatography
system.
- Wavelength Range: UV range 254 nm, VIS range 550 nm
- Type: UV/VIS Detector
- Pharmaceutical Application: Photometric determination of light-absorbing substances in the
UV/VIS range. Ideal for chemicals and flammable samples.
- Wavelength Range: UV range 254 nm,
VIS range 550 nm
- Type: Microprocessor-controlled Digital Signal Processing (DSP technology)
- Pharmaceutical Application: Its function is to make precise determinations of electroactive substances in the mobile phase of an IC system or of a general liquid chromatography system.
- Wavelength Range: Inquire
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