Pharmaceutical Liquid Chromatography Mass Spectrometer (LC/MS Instrumentation)

Liquid chromatography/mass spectroscopy (LC/MS) is a versatile analytical method commonly employed during all phases of pharmaceutical drug development because of its regarded speed, sensitivity, and selectivity. It is commonly used during final analyses of the drug approval process. LC/MS identifies proteins, detects metabolites, determines the molecular weight of drugs, verifies molecular structures and detects for impurities and degradants. Purchasing considerations for pharmaceutical LC/MS systems include the desired ionization method, instrument size, ease of use and operation, and the laboratory budget.

CompanyShimadzu Scientific InstrumentsShimadzu Scientific InstrumentsShimadzu Scientific InstrumentsShimadzu Scientific Instruments
ItemLCMS-8060NX Triple Quadrupole Liquid Chromatograph Mass SpectrometerLCMS-8050 Triple Quadrupole LC/MS/MS Mass SpectrometerNexera Mikros Microflow LC-MS/MSNexera QX Multiplex LCMS
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DescriptionThe LCMS-8060NX utilizes proprietary technologies and more efficient ion transfer to achieve outstanding speed and sensitivity. Incorporation of a new IonFocus electrospray unit and newly designed ion guides deliver robust operation through reduced Incorporating Shimadzu’s proprietary ultrafast technologies (UF Technologies), the new triple quadrupole LCMS-8050 dramatically improves analytical throughput with the ultimate in high-speed performance. In addition, the newly designed ion source andNexera Mikros, a Shimadzu microflow LC/MS system, offers a balanced solution to increased sensitivity with less compromise to throughput and robustness, using flow rates from 1 to 500 µL/min and column I.D. from 0.1 to 1 mm. It achieves stable and The Nexera QX Multiplex LC-MS/MS System uses multiple, alternating sample introduction streams for continuous operation of the mass spectrometer to significantly increase laboratory throughput and profitability.

  • Multiple stream technology
TypeInquireTriple Quadrupole, LC/MS/MSInquireInquire
Pharmaceutical ApplicationInquireScreening of 12 Toxicological DrugsInquireInquire
Sample StateInquireInquireInquireInquire
ResolutionInquireInquireInquireInquire
Ionization Method(s)InquireESIInquireInquire
Mass RangeInquireInquirelMS mass range: m/z 650 to 70000
MSn mass range: m/z 350 to 5000
Inquire
Scanning SpeedInquire30,000 u/secInquireInquire
Regulatory ComplianceInquireInquireInquireInquire
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