Pharmaceutical Liquid Chromatography Mass Spectrometer (LC/MS Instrumentation)

Liquid chromatography/mass spectroscopy (LC/MS) is a versatile analytical method commonly employed during all phases of pharmaceutical drug development because of its regarded speed, sensitivity, and selectivity. It is commonly used during final analyses of the drug approval process. LC/MS identifies proteins, detects metabolites, determines the molecular weight of drugs, verifies molecular structures and detects for impurities and degradants. Purchasing considerations for pharmaceutical LC/MS systems include the desired ionization method, instrument size, ease of use and operation, and the laboratory budget.

CompanyShimadzu Scientific InstrumentsShimadzu Scientific InstrumentsShimadzu Scientific Instruments
ItemLCMS-8045 Triple Quadrupole Liquid Chromatograph Mass SpectrometerNexera Mikros Microflow LC-MS/MSNexera QX Multiplex LCMS
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DescriptionThe triple quadrupole LCMS-8045 is the workhorse instrument in the Shimadzu LC-MS/MS lineup, designed to be analyzing samples around the clock. The heated ESI probe, high-temperature heating block, heated desolvation line, drying gas, and focusing Nexera Mikros, a Shimadzu microflow LC/MS system, offers a balanced solution to increased sensitivity with less compromise to throughput and robustness, using flow rates from 1 to 500 µL/min and column I.D. from 0.1 to 1 mm. It achieves stable and The Nexera QX Multiplex LC-MS/MS System uses multiple, alternating sample introduction streams for continuous operation of the mass spectrometer to significantly increase laboratory throughput and profitability.

  • Multiple stream technology
Mass RangeInquirelMS mass range: m/z 650 to 70000
MSn mass range: m/z 350 to 5000
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