Pharmaceutical Liquid Chromatography Mass Spectrometer (LC/MS Instrumentation)

Liquid chromatography/mass spectroscopy (LC/MS) is a versatile analytical method commonly employed during all phases of pharmaceutical drug development because of its regarded speed, sensitivity, and selectivity. It is commonly used during final analyses of the drug approval process. LC/MS identifies proteins, detects metabolites, determines the molecular weight of drugs, verifies molecular structures and detects for impurities and degradants. Purchasing considerations for pharmaceutical LC/MS systems include the desired ionization method, instrument size, ease of use and operation, and the laboratory budget.

CompanyShimadzu Scientific InstrumentsShimadzu Scientific InstrumentsShimadzu Scientific Instruments
ItemLCMS-8050 Triple Quadrupole LC/MS/MS Mass SpectrometerLCMS-8060NX Triple Quadrupole Liquid Chromatograph Mass SpectrometerNexera Mikros Microflow LC-MS/MS
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DescriptionIncorporating Shimadzu’s proprietary ultrafast technologies (UF Technologies), the new triple quadrupole LCMS-8050 dramatically improves analytical throughput with the ultimate in high-speed performance. In addition, the newly designed ion source andThe LCMS-8060NX utilizes proprietary technologies and more efficient ion transfer to achieve outstanding speed and sensitivity. Incorporation of a new IonFocus electrospray unit and newly designed ion guides deliver robust operation through reduced Nexera Mikros, a Shimadzu microflow LC/MS system, offers a balanced solution to increased sensitivity with less compromise to throughput and robustness, using flow rates from 1 to 500 µL/min and column I.D. from 0.1 to 1 mm. It achieves stable and
TypeTriple Quadrupole, LC/MS/MSInquireInquire
Pharmaceutical ApplicationScreening of 12 Toxicological DrugsInquireInquire
Sample StateInquireInquireInquire
ResolutionInquireInquireInquire
Ionization Method(s)ESIInquireInquire
Mass RangeInquireInquirelMS mass range: m/z 650 to 70000
MSn mass range: m/z 350 to 5000
Scanning Speed30,000 u/secInquireInquire
Regulatory ComplianceInquireInquireInquire
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