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CompanyGattefosséGattefosséGattefosséGattefosséGattefossé
ItemTefose® 63Gelucire® 43/01Gelucire® 44/14Labrafil® M 2125 CSLauroglycolTM 90
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DescriptionPEG-6 stearate (Type I) NF and Ethylene glycol palmitostearate EP/NF/JPE and PEG-32 stearate (Type I) NFHard fat NF/EP/JPELauroyl polyoxyl-32 glycerides NF / Lauroyl macrogol-32 glycerides EP / Lauroyl macrogolglycerides (32) Ch PLinoleoyl polyoxyl-6 glycerides NF / Linoleoyl macrogol-6 glycerides EPPropylene glycol monolaurate (Type II) NF/EP
Final Dosage FormCreams, lotions, ointmentsCapsules, creams, lotions, ointmentsCapsules, emulsions, suspensionsCapsules, emulsions, suspensions, creams, lotions, ointmentsCapsules, emulsions, suspensions, creams, lotions, ointments
FunctionalityNon-ionic O/W emulsifier, low-energy one-pot processing, high mucosal toleranceMatrix-forming agent for protection of APIs sensitive to oxidation, humidity, or light, consistency agent in oral and topical formulationsSolubilizer, bioavailability enhancer, and surfactant in solid dispersions and SMEDDSSolubilizer and bioavailability enhancer for poorly-soluble APIs, self-emulsifier in aqueous fluidSolubilizer, bioavailability and penetration enhancer, water insoluble W/O co-surfactant for SELF and suspensions
Pharmacopeial ComplianceYesYesYesYesYes
TypeBlockPelletsBlockLiquidLiquid
ApplicationTopical, Rectal/VaginalOral, TopicalOralOral, Topical, Rectal/Vaginal, Transdermal, Nasal, ParenteralOral, Topical, Transdermal
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