Cell Culture Media

The purpose of choosing the right cell culture media for pharmaceutical research is to ensure the success and continuation of an active cell culture experiment. Cell culture media typically contains a pH buffer, a food source, a serum, a growth stimulant, and minerals for the metabolic functions of cells. Cell culture media might also contain antibiotic additives.

Next-generation cell culture media formulations are chemically defined (CD) where all the components are identified, and exact concentrations are known. By eliminating undefined ingredients such as serum and hydrolysates, manufacturers have better batch-to-batch consistency and less chance of contamination from adventitious viruses that may lurk in the undefined components during bioprocessing.

Pharmaceutical cell media can be purchased premade to perfectly complement your specific cell line and ensure its optimal growth and longevity based on pre-tested standards. Purchasing considerations for cell culture media include the types of cells being grown, the environment the cells will be exposed to, the chemical additives to be used within the cell-media matrix (for example, the addition of a drug component with specific chemical properties), and ultimately, the size of the cell culturing operation and the allocated budget.

CompanyThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher Scientific
ItemHyCell CHO MediumHyClone CCM5 Cell Culture MediaHyClone CDM4CHO Powder MediaHyClone SFM4CHO-Utility with L-glutamine Cell Culture Liquid MediaHyClone SFX-CHO
Price
Vendor Product PageCompany Product PageCompany Product PageCompany Product PageCompany Product PageCompany Product Page
DescriptionThermo Scientific HyCell CHO Medium is a versatile animal-derived component-free (ADCF) cell culture medium to support the growth of multiple CHO lines and the production of a variety of recombinant proteins without compromising performance. This Thermo Scientific* HyClone CCM5 is a serum-free medium that supports the growth of anchorage-dependent CHO cells. The CHO cell culture platform has led the biopharmaceutical industry in its use of serum-free media (SFM). HyClone has developed a Thermo Scientific HyClone CDM4CHO is a chemically defined, animal-defined component-free (ADCF*) media for therapeutic recombinant protein production without the reliance upon undefined hydrolysates and lipids. HyClone CDM4CHO is a protein-free Thermo Scientific* HyClone SFM4CHO* and SFM4CHO-Utility are high performance cell culture media developed through Metabolic Pathway Design.

Features
  • Support the DHFR selection/amplification system
  • Defined protein-free formulation
Thermo Scientific* HyClone SFX-CHO is an early generation, protein-containing suspension CHO medium.

Features
  • Developed through Metabolic Pathway Design to support superior performance and increased process yields of multiple cell culture platforms
TypePowder Chemically-defined mediaLiquid Serum-free mediaPowder Serum-free Chemically-definedMediaLiquid/Powder Protein-free mediaLiquid Serum-free media
QuantityEAEAEAEAEA
Size(s)5 to 1000 L (Powder) 1 to 500 L (Liquid)500 mL to 200 L (depending on model)5 to 1000 L (depending on model)500mL to 1000 L (depending on model)500mL to 100 L (depending on model)
OriginAnimalAnimalAnimalInquireInquire
Regulatory StatuscGMPcGMPcGMPcGMPInquire
Get quote

Articles