Drug Delivery

Drug delivery is the method in which a pharmaceutical compound is administered to promote a therapeutic effect. Drug delivery routes can include oral, transdermal, nasal, and sublingual application and can directly impact a drugs efficacy. In this drug delivery content hub, you can discover editorial coverage of the latest research and industry trends impacting drug delivery and novel drug discovery.

Shifting Sands: From Sensitivity to Accuracy in Bioanalysis
In recent years, regulatory focus has notably shifted from sensitivity to accuracy, underscoring a pivotal change in how we approach toxicological assessments. While sensitivity remains a critical requirement, our advancing understanding of toxicology has highlighted the crucial need for precise target analysis. This shift in focus is particularly ... read more
Executive Q&A: Biopharmaceuticals/ Biosimilars
The market need is the main driver. Today, access to quality Biologics drugs is limited to a minority of the patients around the world. Increasing the supply of biosimilars worldwide should contribute to making based treatment more available. read more

Oral Drug Absorption - An Understanding of Lymphatic versus Portal Transport and Food Effect
Oral drugs face major challenges like poor solubility, low permeability, and enzymatic degradation, which limit their effectiveness. This article explores cutting-edge strategies to enhance drug absorption through the lymphatic system, including lipid nanoparticles, lipid prodrugs, and food-based approaches. Learn how these ... read more
Whitepaper: Disinfectant Efficacy in cGMP-Compliant Pharmaceutical Manufacturing Settings
The FDA’s intensified onsite inspections of drug production post-pandemic have underscored the importance of robust cleaning- and disinfectant-validation programs. This whitepaper focuses on the importance of disinfectant validations based on real-world conditions to maintain cGMP compliance. It discusses the current lack of ... read more
Nanoparticle Technologies: Enablers for Ocular Drug Delivery
As we continue to discover new and innovative small molecules and therapeutic compounds, over 80% of those candidates in drug pipeline are challenging to development due to their poor solubility and bioavailability. There are several ocular barriers such as tear film, corneal, conjunctival and blood barriers that cause the ... read more
Container Closure Requirements: Preparing for Updates to USP <382>, <661.1>, and <661.2>
This article will give a comprehensive overview of the evolving container closure requirements for parenteral products and insightful exploration of the alterations introduced by USP <661.1>, <661.2>, and <382>, equipping pharmaceutical manufacturers with the essential knowledge to navigate the evolving regulatory compliance standards effectively.... read more
Increasing Pharmaceutical Quality Control with Automation
How can automation improve your QC? This white paper explores the future of QC and automation. Download now to learn more. read more