Drug Delivery

Drug delivery is the method in which a pharmaceutical compound is administered to promote a therapeutic effect. Drug delivery routes can include oral, transdermal, nasal, and sublingual application and can directly impact a drugs efficacy. In this drug delivery content hub, you can discover editorial coverage of the latest research and industry trends impacting drug delivery and novel drug discovery.

Focused Ultrasound’s Therapeutic Potential for Blood-Brain Barrier Opening
Neurological disease accounts for a large share of the global disease burden. CNS drug development, however, remains unusually difficult. One major reason is anatomical, not pharmacological: even a compound with strong target biology has little therapeutic value if it cannot reach the relevant brain tissue at sufficient concentration. read more
Oral Absorption of Peptides and Proteins and Their Role in Drug Pharmacokinetics
Oral bioavailability denotes the fraction of a drug taken orally that arrives in the systemic circulation as an unaltered, active form, and is capable of providing its therapeutic benefit. It is typically presented as a percentage of the amount that enters the bloodstream compared to the administered dose. read more
Beyond Dissolution: Why Today’s BCS Class II Pipeline Requires a More Predictive Approach
Drug molecules are becoming more complex. As pipelines continue to be dominated by poorly soluble compounds, the dynamic of solubility and absorption will remain central to development success. read more
The GLP-1 Boom is Great for Everyone Except Pharma Safety Teams
GLP-1s have generated large amounts of new safety work. Pharmacovigilance systems are struggling to cope with the volume and complexity. read more
Lyophilization and Next-Generation Therapeutics: The Challenges of Scaling Up
Lypophilization helps stabilize fragile new modalities, including messenger RNA and the advanced formulation vehicles that deliver them. read more
Comparative Evaluation of the Efficacy of Glycopyrronium Versus Tiotropium as an Adjunct to Formoterol Therapy in COPD: A Questionnaire-Based Investigation at a Tertiary Care Facility
GFF treatment led to a significant improvement in FEV1% and FEV1/FVC ratios and resulted in faster, more consistent improvements than TFF. read more

ebook: Aseptic Processing Trends and Technologies
eBook offers a variety of strategies to optimize you aseptic fill finish small batch manufacturing to take advantage of the growing market for small-batch biopharmaceuticals. read more
A Green Solution for the Dissolution Laboratory
Going “Green” in today’s business climate where maximizing shareholder equity and conserving capital is a top priority can be difficult, especially if the project increases the overall cost of doing business. read more
A Green Solution for the Dissolution Laboratory
Going “Green” in today’s business climate where maximizing shareholder equity and conserving capital is a top priority can be difficult, especially if the project increases the overall cost of doing business. read more
Why Aren’t We Collaborating with the Personal Care Industry?
As the pharmaceutical industry continues to strive toward modernization, meeting regulatory expectations, and preserving patient safety, organizations are seeing the benefits of intra-industry collaboration and sharing of best practices. read more
Performance of Single-use Virus Filtration at Biopharmaceutical Manufacturing Scale
Commercial manufacturing of biologics such as monoclonal antibodies (mAbs) and recombinant proteins requires robust, reliable processes which cost-efficiently deliver high yields of a safe and effective product. read more

Topical Delivery of Anti-Fungal APIs with Pharmaceutical Grade DMSO
Dimethyl Sulfoxide (DMSO) is one of the most effective, if not the most effective skin permeability enhancers. Delivery of anti-fungal active pharmaceutical ingredients (APIs) topically can be particularly challenging. This webinar will present ... read more