Formulation Development

Pharmaceutical formulation development is the critical step which links the discovery of a novel drug to commercialization. During this step, formulation scientists will determine the best drug delivery vehicle and dosage form needed to deliver a therapeutic effect based on bioavailability or other factors. Below you can explore articles, industry trends, and curated products which can help increase formulation development efficiency.

From Laboratory to Market: Advanced Analytical Approaches in Biopharma
The drug development landscape has undergone a massive transformation in recent years, driven by advancements in bioprocessing and the rise of biologics. Compared to traditional small-molecule drugs, biologics differ significantly in terms of their production methods, molecular complexities and mechanisms of action.1 Their large size and elaborate ... read more
Advancements in Analytical Techniques
As analytical evaluation thresholds (AETs) continue to decrease, advancements in mass spectrometry have enabled us to keep pace with these changes. We can now screen at much lower levels than before, reliably detecting and identifying compounds that are close to the AET. High resolution mass spectrometry both in the LC and GC space have ... read more
Customized Antibodies – Vehicles for Therapeutic Success
They measure only a few nanometers in size, and yet they are our bodies’ first defense line against intruders of all kinds: antibodies are an integral part of our immune system. Since their discovery in the 1890s, science has made huge progress in understanding the mechanisms behind immunoglobulins. read more

ebook: Lipid Excipients to Unlock Oral Bioavailability Issues
Oral dosage forms favor good patient acceptance and compliance in great part because they are easy to take. However, achieving sufficient bioavailability by the oral route can be challenging due to the complexity of the gastrointestinal (GI) tract. read more
Extractables and Leachables Research is Gaining Maturity
The pharmaceutical and medtech industries, along with their associated regulators, are paying increasing attention to testing requirements for extractables and leachables (E&L) to guarantee the safety, quality and efficacy of their products. read more
Manufacturing of Highly Potent APIs with Best-Practice Safety and Containment Control Procedures
It is a key regulatory and safety requirement that prospective hazards associated during the handling of HPAPIs are identified and understood to enable the development of Occupational Exposure Limits (OEL). read more
The NEXT GENERATION in Protein Characterization
The ability to measure and characterize changes in the secondary structure of proteins is critical to many research applications, especially the formulation and development of biotherapeutics. read more
Benefits of Using High-Functionality Excipients in a Continuous Manufacturing Process
As pharmaceutical companies move increasingly toward changing production methods from batch to continuous processing, there is a need to re-evaluate the types and formulations of the excipients used. read more