Formulation Development

Pharmaceutical formulation development is the critical step which links the discovery of a novel drug to commercialization. During this step, formulation scientists will determine the best drug delivery vehicle and dosage form needed to deliver a therapeutic effect based on bioavailability or other factors. Below you can explore articles, industry trends, and curated products which can help increase formulation development efficiency.

Comparative Evaluation of the Efficacy of Glycopyrronium Versus Tiotropium as an Adjunct to Formoterol Therapy in COPD: A Questionnaire-Based Investigation at a Tertiary Care Facility
GFF treatment led to a significant improvement in FEV1% and FEV1/FVC ratios and resulted in faster, more consistent improvements than TFF. read more
Design, Synthesis, Characterization, and ADME Study of Novel 1,2,4-Triazole Derivatives as Anti-Tubercular Agents
In vitro anti-tubercular activity of the two novel 1,2,4-triazole derivatives demonstrated dose-dependent inhibition of Mycobacterium tuberculosis. read more
A Structured Framework for Translating Stage 3b Data Signals into Actionable Intelligence
In commercial manufacturing, the level of effort and assessment need to be proportional to the identified risk. read more
Designing Predictable Pharmaceutical Processes
Bulk solids handling is common in pharmaceutical manufacturing, but it remains one of the most misunderstood and underestimated engineering challenges. read more
Bridging the Polymersome Development Gap
The technical challenges of polymersomes necessitate complex custom synthesis, advanced analytical characterization, and clear pathways to scale up. read more
Review of Vitamin D, Formulations, and Delivery Systems
Deficiencies of vitamin D are present in populations across the world, which emphasizes the need for supplementation and tailored dosing strategies. read more

White paper: Advantages of Antibody-based Selectivity in the Purification of Next Generation Biologics
It has been almost 40 years since the first biologic drug reached the market. That drug was human insulin, which was produced by cloning human genes into E. coli for protein expression at a scale suitable for therapeutic use. read more
eBook: Optimizing Your Biopharmaceutical Processes
eBook offers a complete guide to ensure your biopharmaceutical process produces the highest quality product as efficiently as possible. read more
White Paper: Validation Guidance for Residual Host Cell DNA Testing of Biologics
Assurance of product safety and quality are top of mind for all biotherapeutic manufacturers read more
White Paper: Validation of a Duplex qPCR Assay to Detect Residual Sf9 Host Cell DNA and Baculovirus DNA
Current regulatory authorities (WHO, EMA and US FDA) limited the accepted amounts of residual DNA in biological products making it extremely important to have a sensitive method of quantifying residual host cell DNA. read more
ebook: Lipid Excipients to Unlock Oral Bioavailability Issues
Oral dosage forms favor good patient acceptance and compliance in great part because they are easy to take. However, achieving sufficient bioavailability by the oral route can be challenging due to the complexity of the gastrointestinal (GI) tract. read more

Topical Delivery of Anti-Fungal APIs with Pharmaceutical Grade DMSO
Dimethyl Sulfoxide (DMSO) is one of the most effective, if not the most effective skin permeability enhancers. Delivery of anti-fungal active pharmaceutical ingredients (APIs) topically can be particularly challenging. This webinar will present ... read more
Optimizing SDD Development: Risk-Based Strategies for Spray Dried Dispersion Process Qualification Success
Tony Vickery is a Principal Engineer in the Process and Product Development group at Seràn Bioscience. He leads a team of engineers responsible for developing processes related to particle engineering and enabled drug product intermediates (i.e. ... read more

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CELPHERE MCC Spherical Seed Core

Asahi Kasei
CEOLUS KG Grade Microcrystalline Cellulose

Asahi Kasei
PC-10 Pregelatinized Starch

Asahi Kasei
Soluplus

BASF North America
Captisol - Modified Beta Cyclodextrin

Ligand Pharmaceuticals

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Formulation Development Equipment

Formulation Development Equipment

Drug Delivery Technologies

Drug Delivery Technologies

Particle Analysis and Characterization

Particle Analysis and Characterization

Dissolution Testers

Dissolution Testers

Pharmaceutical Excipients

Pharmaceutical Excipients

Excipient Search Tool

Excipient Search Tool

Excipients by Dosage Form

Excipients by Dosage Form

Active Excipients

Active Excipients