Formulation Development

Pharmaceutical formulation development is the critical step which links the discovery of a novel drug to commercialization. During this step, formulation scientists will determine the best drug delivery vehicle and dosage form needed to deliver a therapeutic effect based on bioavailability or other factors. Below you can explore articles, industry trends, and curated products which can help increase formulation development efficiency.

A Structured Framework for Translating Stage 3b Data Signals into Actionable Intelligence
In commercial manufacturing, the level of effort and assessment need to be proportional to the identified risk. read more
Designing Predictable Pharmaceutical Processes
Bulk solids handling is common in pharmaceutical manufacturing, but it remains one of the most misunderstood and underestimated engineering challenges. read more
Bridging the Polymersome Development Gap
The technical challenges of polymersomes necessitate complex custom synthesis, advanced analytical characterization, and clear pathways to scale up. read more
Review of Vitamin D, Formulations, and Delivery Systems
Deficiencies of vitamin D are present in populations across the world, which emphasizes the need for supplementation and tailored dosing strategies. read more
Advancing Microbial Fermentation for Innovative Biologics
The process is inexpensive and fast, but there are issues with instability, expression, and by-products. Sophisticated technologies target these issues. read more
Freeze-Dried Future: How Lyophilization Is Unlocking Cool Innovations in Pharma
The process is sublime. We all assume that skipping a step in any process can yield suboptimal results. In this case, however, intentionally bypassing the liquid phase of water by going directly from ice to vapor stabilizes a compound without sacrificing its effectiveness, if done correctly. This sublimation is key to freeze-drying or ... read more

A Green Solution for the Dissolution Laboratory
Going “Green” in today’s business climate where maximizing shareholder equity and conserving capital is a top priority can be difficult, especially if the project increases the overall cost of doing business. read more
Why Aren’t We Collaborating with the Personal Care Industry?
As the pharmaceutical industry continues to strive toward modernization, meeting regulatory expectations, and preserving patient safety, organizations are seeing the benefits of intra-industry collaboration and sharing of best practices. read more
Performance of Single-use Virus Filtration at Biopharmaceutical Manufacturing Scale
Commercial manufacturing of biologics such as monoclonal antibodies (mAbs) and recombinant proteins requires robust, reliable processes which cost-efficiently deliver high yields of a safe and effective product. read more
An Update for Pharmaceutical Stress Testing Enabled by Modern Informatics Technologies
Stress testing or forced degradation is a fundamental part of drug development, specifically related to purity through control of stability. read more
Automated Endotoxin Testing: ENDOZYME® II GO Recombinant Factor C Assay and the ASSIST PLUS Pipetting Robot
The ENDOZYME® II GO rFC assay was recently introduced by bioMérieux, featuring a novel 96-well microplate, GOPLATE™, reducing manual handling and enabling a higher degree of consistency. read more

Recent Advances in Crystalline Polymorphism Research in Drug Development
This webinar explores recent advancements in crystal screening and characterization for pharmaceutical development. read more
Speed Meets Precision: Fast Raw Material ID & Advanced Peptide Characterization
As the demand for therapeutic synthetic peptides—such as GLP-1 receptor agonists—continues to surge, biopharmaceutical manufacturers are under increasing pressure to scale production efficiently while maintaining rigorous quality standards. This ... read more
Building Agile Aseptic Operations with Skilled Teams and Smart Tech
The biopharma world is evolving rapidly, driven by rising demand for biologics and advanced therapeutics. To stay ahead, companies are adopting smart technologies and empowering teams to embrace new production methods while meeting strict regulatory ... read more