Formulation Development

Pharmaceutical formulation development is the critical step which links the discovery of a novel drug to commercialization. During this step, formulation scientists will determine the best drug delivery vehicle and dosage form needed to deliver a therapeutic effect based on bioavailability or other factors. Below you can explore articles, industry trends, and curated products which can help increase formulation development efficiency.

Digital Clinical Trial Success Persuades CAUTION to be Replaced by ADOPTION
In clinical research, there is no such thing as ‘taking a leap of faith’ and yet the industry’s need for empirical certainty can sometimes thwart adoption of important innovation. Understandably, the life sciences industry traditionally only takes incremental, calculated chances based on scientific hypotheses, slowing progress while patients – on ... read more
From TB to Today – An Evolution of Public Health
The human body is pretty amazing. It can heal itself, adapt to change, and provide mechanisms to rid itself of bad stuff. Of course, there are many instances when the body needs help, and medicines step in to take care of what the body can’t. Our current technologies to fight disease and sickness are truly amazing. I only need to refer you to ... read more
Emerging Roles of Nucleic Acid-Based Methods in Pharmaceutical Microbiology
New technologies based on the detection and sequencing of nucleic acids are emerging rapidly leading to questions about their best applications, validation requirements, limitations, cost, and implementation. Although the focus of this commentary is largely on pharmaceutical microbiology the status of nucleic acid-based methods in environmental, ... read more

ebook: Lipid Excipients to Unlock Oral Bioavailability Issues
Oral dosage forms favor good patient acceptance and compliance in great part because they are easy to take. However, achieving sufficient bioavailability by the oral route can be challenging due to the complexity of the gastrointestinal (GI) tract. read more
Extractables and Leachables Research is Gaining Maturity
The pharmaceutical and medtech industries, along with their associated regulators, are paying increasing attention to testing requirements for extractables and leachables (E&L) to guarantee the safety, quality and efficacy of their products. read more
Manufacturing of Highly Potent APIs with Best-Practice Safety and Containment Control Procedures
It is a key regulatory and safety requirement that prospective hazards associated during the handling of HPAPIs are identified and understood to enable the development of Occupational Exposure Limits (OEL). read more
The NEXT GENERATION in Protein Characterization
The ability to measure and characterize changes in the secondary structure of proteins is critical to many research applications, especially the formulation and development of biotherapeutics. read more
Benefits of Using High-Functionality Excipients in a Continuous Manufacturing Process
As pharmaceutical companies move increasingly toward changing production methods from batch to continuous processing, there is a need to re-evaluate the types and formulations of the excipients used. read more