Spectroscopy

Spectroscopy can be used to achieve repeatable, high throughput analysis for impurities, dosage, and stability in finished drug products or raw ingredients. Spectroscopy is a broad term which encompass disciplines such as Raman spectrometers and other techniques including gas chromatography–mass spectrometry (GC–MS) and liquid chromatography–mass spectrometry (LC–MS). In this spectroscopy hub, you can find coverage on the latest pharmaceutical spectroscopy trends, webinars, and products.

A Structured Framework for Translating Stage 3b Data Signals into Actionable Intelligence
In commercial manufacturing, the level of effort and assessment need to be proportional to the identified risk. read more
Designing Predictable Pharmaceutical Processes
Bulk solids handling is common in pharmaceutical manufacturing, but it remains one of the most misunderstood and underestimated engineering challenges. read more
Bridging Legacy DCS and Modern Automation: Automation and Data Standards Reduce Risk
Pharmaceutical manufacturers who use automation and AI models improve processes, scale more quickly, and gain the agility to meet shifting market demands. read more
Editor's Top Tech November/December 2025
With the end of 2025 approaching, we have compiled a list of this quarters top tech. read more
Understanding Drug Delivery from Spectroscopic Insights
This article explores drug delivery routes in the human body and highlights advanced spectroscopic methods - such as Raman, infrared, fluorescence, and nonlinear techniques - for investigating delivery mechanisms. It emphasizes their industrial relevance and presents an outlook on how these tools can accelerate drug development and precision in ... read more
Recombinant Lysate Manufacture: Considerations for Contamination Control
Pyrogens in general (including lipoteichoic acids, CpG DNA, viruses, and flagellin), and Gram-negative bacteria that release endotoxin, present a risk for pharmaceutical products that are administered in ways that bypass the body’s natural defenses, especially those that are infused into the bloodstream. This concern exists since endotoxin ... read more

Non-Destructive Hardness Testing
Tablet hardness testing plays an important role in pharmaceutical product development and quality control. In the race to streamline tablet hardness analysis, Advantest combines speed, simplicity and increased precision with innovative and non-destructive terahertz (THz) metrology. Read how THz spectroscopy evaluates tablet ... read more
Spectroscopic Characterization of Nanoparticles for Potential Drug Discovery
The inertness and biocompatibility of gold nanoparticles (Au-NPs) make them very promising for specific applications such as medical imaging, drug delivery, gene delivery, and molecular sensing. This study evaluates the use of spectroscopic techniques, such as UV-Vis and FTIR, to monitor and characterize gold nanoparticles and ... read more

Speed Meets Precision: Fast Raw Material ID & Advanced Peptide Characterization
As the demand for therapeutic synthetic peptides—such as GLP-1 receptor agonists—continues to surge, biopharmaceutical manufacturers are under increasing pressure to scale production efficiently while maintaining rigorous quality standards. This ... read more
Optimizing SDD Development: Risk-Based Strategies for Spray Dried Dispersion Process Qualification Success
Tony Vickery is a Principal Engineer in the Process and Product Development group at Seràn Bioscience. He leads a team of engineers responsible for developing processes related to particle engineering and enabled drug product intermediates (i.e. ... read more
Comprehensive Characterization of mAb Charge Variants, PTMs, and CQAs Using A Microfluidic CE/MS System
Accurate characterization of charge variants and other critical quality attributes (CQAs) is essential for therapeutic mAb development and manufacturing. This webinar introduces the ZipChip microfluidic capillary electrophoresis system coupled with ... read more