Spectroscopy

Spectroscopy can be used to achieve repeatable, high throughput analysis for impurities, dosage, and stability in finished drug products or raw ingredients. Spectroscopy is a broad term which encompass disciplines such as Raman spectrometers and other techniques including gas chromatography–mass spectrometry (GC–MS) and liquid chromatography–mass spectrometry (LC–MS). In this spectroscopy hub, you can find coverage on the latest pharmaceutical spectroscopy trends, webinars, and products.

Analytical Method Development with a Practical Risk Assessment Program that Enhances Commercial QC Robustness
Active pharmaceutical ingredient process development requires comprehensive analytical controls utilizing a wide range of analytical methods. An analytical risk survey program was previously developed to evaluate common risk factors in the analytical control strategy for early to mid-stage development. For late-stage and the development of ... read more
Chiral Separation and Enantiomeric Analysis: Critical Importance in Pharmaceutical Development
Chiral separation has become a cornerstone of modern pharmaceutical development as the industry increasingly recognizes that enantiomers of chiral drugs can exhibit dramatically different biological activities, safety profiles, and therapeutic effects. The regulatory landscape has evolved to strongly favor single enantiomer development over racemic... read more
Advances in Ionizable Lipid Design: Accelerating mRNA Therapeutic Development Through Rapid Optimization Platforms
Recent breakthroughs in ionizable lipid engineering represent a paradigm shift in mRNA therapeutic development, transforming what was once a years-long optimization process into a matter of months. These advances center on sophisticated synthetic platforms that enable rapid generation and screening of diverse ionizable lipid libraries, coupled with... read more

Extractables and Leachables Research is Gaining Maturity
The pharmaceutical and medtech industries, along with their associated regulators, are paying increasing attention to testing requirements for extractables and leachables (E&L) to guarantee the safety, quality and efficacy of their products. read more
Objectionable Microorganisms: Keeping Bad Bugs Out of Good Products
No pharmaceutical company wants to sell a non-sterile drug contaminated with objectionable microorganisms, but how does a company know which organisms are objectionable and how do they ensure their drugs do not contain them? read more
Automated Morphological Imaging: Deeper Insight into your Pharmaceutical Formulation or Product
Fully-automated morphological imaging of a pharmaceutical formulation or product can deliver particle size and shape information in a single measurement, and with minimal user intervention. read more
Challenging the Microbial Sanitization of a Liquid Chromatography System
In developing biologics or biotherapeutics, a great deal of effort is used to ensure that none of the contaminating or hazardous residual components from the organisms responsible for protein expression remain after purification. read more
Closure and Stopper Systems: Getting Big Benefits from Small Components
Protecting your liquid transfer processes—and your investment in biopharmaceutical materials—involves a multitude of components, from tubing and piping, to connectors and filters, to bioreactors and storage vessels. read more