Excipients

Pharmaceutical excipients, which can be functional or inactive ingredients, work to enhance the medically relevant properties of the API. When used to promote ingredient qualities, excipients can be an asset for formulators to increase stability, bulk up the formulation, or enhance the therapeutic effects of the API. Below you can explore helpful resources including editorial coverage and webinars related to pharmaceutical excipients.

Comparison of Optical Spectroscopy Techniques for Pharmaceutical Analysis
The optical spectroscopy toolbox contains a large variety of methods that exploit light-matter interactions such as absorption, emission, and scattering phenomena across the entire electromagnetic spectrum. This work aims at giving an overview of the available techniques and their potential applications for product and process analysis in the ... read more
CIP Failures Due to Biofilm Formation: Strategies for Prevention and Remediation
The aim of a Clean-in-Place (CIP) system is to remove all undesirable materials from product contact surfaces to a level such that residues remaining are of minimal risk to the safety or quality of the product. While the general focus is on the removal of product residues or chemical residues, there is often a microbial control element involved. ... read more
Comparing an Inspection by a Regulator to an Investigation by a Pharma Company
Recently, there has been an increased focus on contamination control activities for pharmaceuticals due to updated requirements in the European Union’s Annex 1 Update. (EU, 2022). The recent update of Annex 1 (ISO 14644-1, 2022) has specified the need for a contamination control strategy for both sterile and non-sterile products. Recently, a ... read more

Hydroxypropyl Cellulose for Orally Disintegrating Film Drug Application
Hydroxypropyl cellulose (HPC) is a water-soluble polymer that has film formation properties with excellent plasticity. Its hydroxypropyl groups drive the solubilization of the cellulose thus hindering the hydrogen bonding of the hydroxyl groups. In this study, we evaluated the applicability and effectiveness of HPC in Orally ... read more