eBook: Proven Applications Using Variable Pathlength Spectroscopy

This eBook provides details and insight into using Slope Spectroscopy and the CTech™ SoloVPE® variable pathlength spectroscopy system. The SoloVPE® system provides a rapid, robust, and repeatable, non-disruptive concentration measurement method for proteins, plasmid DNA, and nucleic acid modalities. Articles in this eBook cover a variety of topics including viral filtration integrity, polysorbate UV-Vis spectral and slope analysis, how to measure Co-Oximetry parameters in bovine hemoglobin, accurately calculating the plasmid DNA purity ratio in human gene therapy products, techniques for real-time biomanufacturing process monitoring, and the application of in-line variable pathlength chromatography for high-concentration oligonucleotide solutions.

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  • Slope Spectroscopy uses patented variable pathlength technology to accurately measure various targeted concentrations in biopharma manufacturing, both at-line (SoloVPE) and in-line (FlowVPX). Would you like a Repligen analytics specialist to contact you to learn more?*

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