DynaPro™ ZetaStar™ DLS Instrument

The DynaPro ZetaStar instrument from Wyatt Technology™ a portfolio of Waters Corporation, was designed to support workflows in gene therapy, vaccine, mRNA, protein, and nanoparticle development. The ZetaStar instrument simultaneously measures dynamic and static light scattering and dynamic and electrophoretic light scattering (DLS/SLS/ELS) all in one device. By combining multiple techniques, a scientist can efficiently measure particle size, polydispersity, zeta potential/charge, turbidity, and molecular weight all in one system with as little as 2 µL of sample.

Features, Benefits, and Specifications

The ZetaStar Instrument allows scientists to collect five critical parameters in a single workflow: size, polydispersity, particle concentration, zeta potential, and turbidity while requiring as little as 2 µL and performing these measurements in high salt solutions, as much as 2x greater than physiological conditions.

Applications

Designed to support the expanding needs of biopharma formulation and development laboratories, the ZetaStar instrument helps scientists working in gene therapy, vaccines, mRNA, and proteins develop more stable therapies. It can also benefit R&D laboratories in material science investigating the colloidal stability of novel molecules like quantum dots or other metal nanoparticles used in semiconductor applications.