Katalyst D2D® (Design-to-Decide) is a browser-based software application that fully digitalizes automated experimentation by integrating experimental hardware, analytical instruments, and third-party software across end-to-end workflows. It consolidates contextualized, structured data from design-make-test-analyze (DMTA) cycles into a single interface to support faster, higher-confidence decision-making in pharmaceutical R&D. Purpose-built for high-throughput experimentation, process optimization and scale-up, and materials/preformulation studies, Katalyst D2D streamlines experiment design, execution, and analysis while ensuring data integrity and traceability. The normalized data Katalyst manages can be used directly to build AI/ML models, enabling organizations to accelerate future experimentation and digital transformation initiatives.
Features and Benefits
The software delivers integrated experiment lifecycle management—design, planning, execution, analysis, and reporting—in a single, chemically intelligent, browser-based environment that is always up to date and supports thin-client deployment for IT teams. It uniquely integrates robotic platforms, lab reactors, plate-based systems, and a wide range of analytical instruments, as well as third-party informatics systems, bringing all experiment data and associated context together. Workflow automation is supported through machine-readable instruction lists for robots and instruments, automatic analytical data processing, and flexible visualization, which collectively reduce manual effort and shorten DMTA cycle times. By minimizing manual transcription, Katalyst D2D strengthens data integrity and compliance readiness, while its AI/ML-ready data structures allow organizations to route curated experimental datasets directly into data science and predictive modeling workflows. Deployed in your Cloud environment, it offers scalable administration and integration tools to support global development teams.
Applications
Katalyst D2D is used to streamline high-throughput synthesis in discovery and development, enabling rapid setup, execution, and analysis of reaction screens while capturing all relevant reaction metadata for reuse.
In CMC process development, it supports synthetic route optimization, process scale-up in lab and pilot reactors, and in situ monitoring to establish robust, scalable manufacturing processes more efficiently.
For materials and preformulation studies, Katalyst D2D manages solid-form screening, solubility and stability assessments, and characterization of thermal and physical properties, automatically assembling critical process parameters and attributes needed for decision-making and regulatory documentation.
Its shared, digital environment also supports cross-functional pharmaceutical development programs by enabling project teams to collaborate around a single, structured experimental data backbone that shortens the path from discovery experiments to clinical trial–ready processes.