JetX is an automated sample preparation platform designed to standardize and accelerate assay and content uniformity testing in pharmaceutical laboratories. Its patented JetXtraction™ technology uses a continuous high-velocity jet of solvent to rapidly disintegrate and extract APIs, integrating extraction, filtration, and dilution into a single programmable sequence. Up to 30 samples can be prepared in parallel, scaling to 120 per shift on the MultiFlow configuration, while using the same validated analytical methods already established in the lab, requiring no analytical method revalidation. By minimizing manual intervention, JetX delivers up to 4× faster preparation with 80% less hands-on labor, making it well suited to high-throughput, GMP-regulated environments.
Features and Benefits
JetX combines solvent delivery, jet driven extraction, in-line filtration, and precise dilution into a closed, benchtop system that delivers ready-to-inject samples directly into standard HPLC or UHPLC vials or well plates. An intuitive JetPilot touchscreen interface supports preconfigured methods and guided setup, lowering training requirements and enabling consistent execution across users. Integrated self-cleaning routines between batches reduce carryover risk and minimize routine maintenance. The platform’s AutoDI data integrity framework securely records preparation parameters, events, and user actions in a 21 CFR Part 11 compliant manner, with audit trails, electronic signatures, and connectivity to LIMS and chromatography data systems. Together, these features provide substantial reductions in total preparation time and analyst labor while maintaining precision comparable to manual workflows.
Applications
JetX is particularly suited for routine quality-control testing of solid oral dosage forms, including tablets, capsules, and powders, as well as semi-solids and liquid formulations via its specialized extraction cell designs. Because it preserves existing analytical procedures unchanged, it can be adopted with minimal revalidation effort while providing immediate gains in throughput and consistency. Beyond routine QC, methods developed on the single-core SingleFlow unit transfer directly to the five-core MultiFlow without re-validation of the analytical principle, giving organizations a seamless path from method development through production-scale deployment across multiple laboratories.