Rapid Mycoplasma Testing by Anyone, Anywhere, at Any time
The BIOFIRE® SPOTFIRE® Industry System is designed to enable rapid, in-house mycoplasma detection for biopharmaceutical manufacturing environments. By delivering results in less than one hour through a fully automated, closed-system workflow, the platform allows testing to be performed closer to production operations without the need for specialized molecular expertise. The system supports testing across raw materials, in-process samples, and finished products, helping accelerate quality decision-making. Its streamlined operation and integrated data capabilities aim to enhance efficiency while maintaining compliance with data integrity requirements.
Features and Benefits
The BIOFIRE® SPOTFIRE® System integrates automated extraction, amplification, and detection within a single instrument, reducing manual intervention and simplifying traditionally complex molecular workflows. Its closed-system design and automated workflow make rapid mycoplasma testing accessible without requiring specialized molecular expertise. Built-in barcode scanning, electronic signatures, and customizable user access support traceability and regulatory compliance, while bidirectional LIMS connectivity and advanced cybersecurity architecture enable seamless integration into modern IT environments.
The platform’s compact, stackable design—supporting up to four modules—allows manufacturers to scale testing capacity without expanding laboratory space. The system is designed for use with the BIOFIRE® Mycoplasma Panel, providing a standardized, automated workflow that simplifies routine mycoplasma testing. Overall, the system supports faster contamination detection, improves operational flexibility, reduces reliance on specialized personnel, and strengthens data integrity, enabling earlier intervention in the event of potential mycoplasma contamination.
Applications
The BIOFIRE® SPOTFIRE® System is suited for a range of mycoplasma testing applications across biopharmaceutical manufacturing workflows. It can be used for raw material testing, in-process monitoring, and final product release, supporting comprehensive quality control programs. The system is also applicable across biopharmaceutical manufacturing workflows where timely mycoplasma results can help support production continuity and faster quality decisions
Additionally, the platform enables organizations to transition from outsourced to in-house mycoplasma testing, improving turnaround times and operational control. Its ability to deliver rapid, reliable results with enhanced traceability makes it well-suited for manufacturers seeking to modernize quality testing while maintaining compliance and efficiency.