Single-pass tangential flow filtration (SPTFF) has emerged as an effective method for speeding up manufacturing processes. In this application note, SPTFF preconcentration is used to intensify anion exchange polishing in monoclonal antibody processing, improving impurity removal and column productivity. Learn how linking this intensified mAb polishing approach with upstream steps can lead to a more continuous process, which eliminates tankage and hold time and enables the use of smaller polishing columns to improve product quality at higher throughputs.

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Application Note: Intensified Monoclonal Antibody Production

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