The use of mRNA to produce the next generation of vaccines and therapeutics is growing rapidly. However, more efficient manufacturing methods are needed to bring these vital novel therapeutics to market quickly and with the highest efficacy. The capping methodology used is critical to the success of mRNA-based therapies: without a 5’ cap, appreciable levels of translation cannot take place. This infographic summarizes several different mRNA capping technologies, focusing on how the latest capping methodology can increase product quality and speed-to-market for the industry.