Despite advances in drug development, achieving a true in vitro–in vivo correlation (IVIVC) for subcutaneous (SC) drugs remains difficult. However, innovative in vitro models like SCISSOR are helping bridge the gap, offering new insights into drug release and injection-site behavior. This infographic explores the current challenges and emerging solutions driving progress toward reliable IVIVC in SC drug development. Download now to explore how innovations are narrowing the gap to true IVIVC every day.