Pharmaceutical sample digestion involves the chemical reaction of a sample with reagents to remove the sample matrix and leave components suspended in solution. The sample and reagents are heated in an appropriate container to speed the reaction. During digestion, there is always some temperature variation, the result of microwave field flux variabilities, differing microwave absorption rates among the samples, and chemical reactions during digestion of the sample. This is why the process is sometimes called microwave digestion.
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