The PHCbi Cell-IQ™ CO2 Laboratory Incubator MCO-170AICUVHLPA is a sophisticated cell culture incubator designed to replicate the ideal cell culture conditions needed to grow cells and associated products for biological analysis.

Features, Benefits and Specifications

The PHCbi Cell-IQ™ CO2 Laboratory Incubator offers advanced features for precise cell culture control.

The Cell-IQ CO2 Laboratory Incubator features an InCusaFe® germicidal interior, which offers significant benefits for contamination prevention and control. The copper-enriched stainless-steel alloy provides germicidal properties that inhibit microbial growth while maintaining corrosion resistance. This innovative material contributes to active background decontamination methods, is easy to maintain, resists discoloration as observed with pure copper interiors, and provides ongoing passive protection throughout the chamber.

The SafeCell™ UV system works in tandem with the InCu-saFe interior to provide comprehensive contamination control. While the InCu-saFe interior offers passive, continuous antimicrobial protection, the SafeCell UV system actively decontaminates circulating air and the water within the humidity reservoir. This multi-level approach ensures continuous protection, with the UV system activating automatically after door openings to eliminate introduced contaminants without interfering with cell cultures.

The dual beam infrared (IR) sensor plays a crucial role in regulating CO2 levels within the incubator. Utilizing nondispersive infrared technology, the sensor provides precise and reliable CO2 measurements. Its dual beam wavelength design allows for continuous auto-zero calibration and compensation for environmental factors. The sensor enables rapid and accurate CO2 recovery1 without overshoot, maintains long-term stability, and ensures specificity in CO2 detection regardless of changes in relative humidity. This advanced technology is essential for maintaining optimal pH levels in cell culture media and ensuring consistent and repeatable experimental conditions.

The Cell-IQ CO2 Laboratory Incubator includes an integrated hydrogen peroxide (H2O2) decontamination system that effectively cleans the chamber by utilizing vaporized hydrogen peroxide. This system achieves a 100% kill rate2 with a 6-log reduction of contaminants in under three hours, offering a significantly faster turnaround compared to traditional dry heat sterilization methods.3 This efficient decontamination process ensures a quick return to cell culture, while maintaining a sterile environment essential for sensitive cell culture applications. Lab Incubator for Cell Culture PHCbi

Applications

The Cell-IQ CO2 Laboratory Incubator is designed for a wide range of demanding and highly regulated applications in biomedical, pharmaceutical, medical research, and clinical laboratory settings. Some key applications include:

  • Stem cell research: The precise environmental control is crucial for maintaining stem cell cultures.
  • Tissue engineering: The incubator provides optimal conditions for growing engineered tissues.
  • Genetic research: Stable conditions are necessary for genetic manipulation and analysis.
  • Regenerative medicine: The incubator supports the growth of cells for regenerative therapies.
  • Cell-based assays: Consistent conditions ensure reliable results in various cell-based experiments. • Cancer research: The incubator allows for the study of cancer cells under controlled conditions.
  • Drug development and testing: It provides a stable environment for evaluating drug effects on cell cultures.
  • Hypoxia studies: The O2 control feature allows researchers to simulate low-oxygen environments.
  • Continuous Metabolic Analysis: The LiCellMo Live Cell Metabolic Analyzer, when used in conjunction with the MCO-170AICUVHL CO2 incubator, enables continuous metabolic analysis of cells by providing real-time monitoring of glucose and lactate levels in the culture medium.

References

  1. https://markitbiomedical.com/knowledge-center/files/11568_2_ PHCBI_IR_vs_TC_Sensors_Feature_Note_vf.pdf, Page 3
  2. https://markitbiomedical.com/knowledge-center/files/MCO_ Whitepaper_Final0308_2.pdf “Independent Test Results Document the Efficacy of H2O2 Technique” Test Result: No growth was observed for any of the biological indicators after decontamination of the inner chamber by hydrogen peroxide gas certified below. Testing Institution: Confidential test report No.17/049 carried out by Public Health England on 17, April 2018”
  3. https://markitbiomedical.com/ knowledge-center/files/MCO_ Whitepaper_Final0308_2.pdf Page 4