Articles in this Issue
Long Acting Injectables (LAIs) are a drug formulation option that provide a slow and sustained release of the Active Pharmaceutical Ingredient (API) after administration.LAI formulations have several advantages relative to classical oral formulations...
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John Tillotson, Pharmaceutical Technical Business Director, ABITEC Corporation: Primarily, the pandemic has challenged supply chain logistics and increased the manufacturing costs of numerous excipients including controlled-release excipients. This ...
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Use of antibodies for detection of very low analyte concentrations has been evolving since Yalow and Berson developed the radioimmunoassay in the late 1950’s . Despite the tremendous advancements immunoassays provided in clinical science, some ...
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The COVID pandemic brought mRNA vaccines to the forefront of innovation and progress in therapeutical medicine with the rapid release of highly efficacious (93–95%) vaccines by BioNTech/Pfizer and Moderna. Once the sequence of SARS-CoV-2 was ...
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Biotechnology has changed the face of pharmaceutical discovery, research, and development by replacing small molecule drugs with macromolecules produced in cultured cells and microorganisms. Through an equally monumental paradigm shift, Cell- and ...
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Viruses are found in almost every ecosystem on Earth and are the most numerous types of biological entity. As such, viruses pose a challenge to many aspects of biopharmaceutical manufacturing. These challenges not only relate to viruses per se or ...
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Oligonucleotide therapeutics development continues to accelerate with progress in oligonucleotide chemistry and adoption of delivery technologies. This article discusses necessary steps to execute and assure quality of oligonucleotide Active ...
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As the need for fast, efficient, and high-quality bio/pharmaceutical testing services continues to grow, industry service providers are expanding and upgrading their capabilities to best serve their current and future partners.
Eurofins BioPharma ...
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Metabolomics, using Liquid Chromatography-Mass Spectrometry (LC-MS), is one of the most powerful ways to deliver molecular profiles from patient samples. The clear annotation of metabolites enables scientists to accurately characterize biomarkers for...
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Quality Control departments in the pharmaceutical industry often seek new, innovative products to simplify their testing. They want compliant and reliable instruments that are easier for analysts to use and reduce their footprint in the lab. Often, a...
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DataShare Elite is an intuitive software program that provides a convenient way to manage and store Sievers TOC instrument data in a single repository from multiple sites and instruments. This enables pharmaceutical manufacturers to make faster, more...
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Introduction
The intent of this article is to stimulate more conversation and catalyze more improvement across our industry relating to the repeat problems we have seen for literally decades.
During research for the article the author discovered ...
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Cleaning and disinfection of surfaces are not only the essential steps for maintaining the cleanliness and control of the manufacturing environment, but it is also one of the most important pillars of the Contamination Control framework. The overall ...
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The purpose of this column is to highlight and summarize recent key patents in the pharmaceutical arena issued by the US Patent Office in April 2022.
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If you have kids, or grandkids, know any kids, or are a kid at heart and haven’t seen Monster’s Inc. you owe it to that kid in your life to watch this movie with them.
The CG animated movie is based in an alternate reality (of course) where ...
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