White Paper: Real-time Detection of Burkholderia cepacia and Biofilm in Pharmaceutical Water Systems

Senior Field Marketing Manager BioMonitoring

The ability to continuously monitor and quickly detect stressed objectionable organisms, like Burkholderia cepacia, or biofilm growth, within a pharmaceutical water system is of paramount importance. Certain organisms such as B. cepacia can be very difficult to detect with the culture media typically used to assess point-of-use samples. Identifying biofilm growth can be equally tedious, requiring numerous intermittent samples before CFU trends become apparent. Once discovered, both can be difficult to remove and, when incompletely removed, can persist and proliferate. With the use of bio-fluorescent particle counters (BFPC) like the BioVigilant IMD-W™ system, water loop bioburden levels can be monitored continuously and changes and trends in bioburden detected more quickly. Data is shared on the IMD-W system’s counting sensitivity to B. cepacia and use of this online water bioburden analyzer (OWBA) as a predictive monitoring tool in the detection of biofilms and stressed organisms.

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