Description
Nefopam is a non-opioid, non-steroidal, centrally acting analgesic drug that is derivative of the non-sedative benzoxazocine. Although the mechanisms of analgesic action of Nefopam are not well understood, they are similar to those of triple neurotransmitters (serotonin, norepinephrine, and dopamine) reuptake inhibitors, and anticonvulsants. It has been used mainly as an analgesic drug for nociceptive pain, as well as a treatment for the prevention of postoperative shivering and hiccups. Based on Nefopam's mechanisms of analgesic action, it is more suitable for the treatment of neuropathic pain.